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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK11
All Species:
18.18
Human Site:
S401
Identified Species:
28.57
UniProt:
Q15831
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15831
NP_000446.1
433
48636
S401
G
T
E
A
A
Q
L
S
T
K
S
R
A
E
G
Chimpanzee
Pan troglodytes
XP_524028
433
48572
S401
G
T
E
A
A
Q
L
S
T
K
S
R
A
E
G
Rhesus Macaque
Macaca mulatta
XP_001093806
433
48511
S401
G
T
E
A
A
Q
L
S
T
K
S
K
A
E
G
Dog
Lupus familis
XP_542206
439
49298
S407
S
A
Q
L
S
T
K
S
K
V
E
R
R
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK7
436
49248
S404
G
T
E
P
Q
L
S
S
K
V
K
P
E
G
R
Rat
Rattus norvegicus
NP_001101539
436
49227
S404
G
T
E
P
Q
L
S
S
K
V
K
P
E
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519859
324
36639
P293
E
P
L
V
P
I
P
P
G
P
E
T
K
D
R
Chicken
Gallus gallus
Q0GGW5
440
49774
S405
G
T
E
P
G
Q
L
S
T
K
S
K
A
E
R
Frog
Xenopus laevis
Q91604
432
49054
S400
L
C
M
N
G
T
E
S
Q
L
K
T
E
R
R
Zebra Danio
Brachydanio rerio
NP_001017839
440
49807
P408
T
E
S
A
A
L
K
P
K
C
E
R
R
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650302
567
62874
E535
L
G
N
G
S
R
E
E
A
P
V
K
K
K
G
Honey Bee
Apis mellifera
XP_623596
434
50409
S397
L
Q
E
M
D
K
I
S
E
D
Q
K
T
T
W
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
G545
E
D
S
A
A
P
L
G
P
Q
R
R
P
S
S
Sea Urchin
Strong. purpuratus
XP_780778
429
48923
E396
D
A
P
Q
I
V
V
E
P
D
E
S
S
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
L464
N
S
S
A
D
G
M
L
S
N
S
M
H
D
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
92.4
N.A.
90.1
90.5
N.A.
57.7
89.3
81.2
82.2
N.A.
41.4
54.6
29.8
57.7
Protein Similarity:
100
99.3
99.5
94.5
N.A.
93.3
93.1
N.A.
63.2
93.1
87.5
87.2
N.A.
54.8
71.8
43.7
72.2
P-Site Identity:
100
100
93.3
13.3
N.A.
26.6
26.6
N.A.
0
73.3
6.6
20
N.A.
6.6
13.3
26.6
0
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
26.6
N.A.
6.6
80
6.6
20
N.A.
33.3
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
40
34
0
0
0
7
0
0
0
27
7
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
7
0
0
14
0
0
0
0
14
0
0
0
20
0
% D
% Glu:
14
7
47
0
0
0
14
14
7
0
27
0
20
27
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
40
7
0
7
14
7
0
7
7
0
0
0
0
14
27
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
7
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
14
0
27
27
20
27
14
7
0
% K
% Leu:
20
0
7
7
0
20
34
7
0
7
0
0
0
0
0
% L
% Met:
0
0
7
7
0
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
7
7
0
0
0
0
0
7
0
0
0
0
7
% N
% Pro:
0
7
7
20
7
7
7
14
14
14
0
14
7
0
7
% P
% Gln:
0
7
7
7
14
27
0
0
7
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
7
34
14
7
34
% R
% Ser:
7
7
20
0
14
0
14
60
7
0
34
7
7
14
20
% S
% Thr:
7
40
0
0
0
14
0
0
27
0
0
14
7
7
0
% T
% Val:
0
0
0
7
0
7
7
0
0
20
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _